Primary small cell lung cancer (SCLC) showing epidermal growth factor receptor (EGFR) mutation is extremely rare. Transformation into SCLC has been reported as an evolution of lung adenocarcinoma acquiring resistance to EGFR tyrosine kinase inhibitors (TKI) and is considered to be a rare resistance mechanism of EGFR-TKI therapy.
NIH Funded Articles
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
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Handwriting is a uniquely human trait which progresses and evolves during lifetime and declines with age. The aim of the present paper is to assess variation in handwriting features with age among female writers of select population groups of Delhi, India (for Roman script).
The Mediterranean Sea is catalogued worldwide as one of the 25 “hot spots” in terms of biological diversity . However, it hosts many threatened species including turtles, marine mammals, rays and sharks, with chondrichthyans being the group exposed to the highest risk, with 42% of the species living under some type of threat . On the other hand, a third of the other species studied in these waters, are not under any apparent risk .
Brain water metabolism ensures the processes of cellular communication, the transit of the signaling molecules, neurotransmitters, cytokines, and substrates, participates in the clearance of pathogenic metabolites. Many neurological conditions that present serious clinical problems arise from the altered fluid flow (e.g. Alzheimer’s disease, idiopathic normal pressure hydrocephalus, migraine, traumatic brain injury and stroke).